Cleanliness is an essential factor that is critical to ensure the biological safety cabinet's efficacy. Regular cleaning helps maintain cleanliness, reducing the potential spread of harmful particulates, bacteria, and other contaminants.

Materials used in the construction of biological safety cabinets must be corrosion-resistant, easy to clean, and non-porous to prevent bacterial growth. The materials must also be durable enough to withstand the required cleaning and decontamination procedures.

The entire BSC must meet the specified international standards, including ISO 14644-1 and EN1822. The cabinets must be tested regularly, and proper documentation of testing and cleaning should be available upon request.

The cleanliness and materials used in the construction of the cabinet is one of the most essential factors in ensuring the success and safety of the experiments being performed.